Sour Cream (Best Option)
1:1 by volumeSour cream is an excellent substitute because it has a similar fat content and acidity level as Greek yogurt, which helps tenderize the gluten and activate baking soda or powder in the recipe. This ensures the pound cake remains moist and rises properly.
When substituting, use equal amounts of sour cream for Greek yogurt. Be mindful that sour cream is slightly less thick, so the batter may be marginally looser but this generally does not affect the final texture.
The final pound cake will have a comparable crumb structure and richness, with a slightly tangier flavor that complements the cake's sweetness without overpowering it.